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1
- Adesanya vs. Strickland
- Sean Strickland | Decision
- 2023 | UFC 293
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IDC what anyone says, this is the biggest upset in MMA history. The other big upsets on this list were still somewhat expected. Pretty much everyone admits to there being a punchers chance in MMA(extend that to subs). Serra v GSP was such an upset. Same with Nunes v Pena, Silva v Weidman, Bisping v Rockhold. No one expected this to be a one sided striking beatdown to someone who is ubiquitously regarded as the best and most sophisticated strikers in the sport. This is #1 guys. Admit it.
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2
- Serra vs. St-Pierre I
- Matt Serra | KO/TKO | Round 1
- 2007 | UFC 69
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3
- Nunes vs. Peña
- Julianna Peña | Submission | Round 2
- 2021 | UFC 269
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4
- Rousey vs. Holm
- Holly Holm | KO/TKO | Round 2
- 2015 | UFC 193
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5
- Silva vs. Weidman
- Chris Weidman | KO/TKO | Round 2
- 2013 | UFC 162
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6
- Rockhold vs. Bisping II
- Michael Bisping | KO/TKO | Round 1
- 2016 | UFC 199
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7
- Barão vs. Dillashaw
- T.J. Dillashaw | KO/TKO | Round 5
- 2014 | UFC 173
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8
- Emelianenko vs. Werdum
- Fabrício Werdum | Submission | Round 1
- 2010 | Strikeforce
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9
- McGregor vs. Diaz
- Nate Diaz | Submission | Round 2
- 2016 | UFC 196
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10
- Gonzaga vs. Filipović
- Gabriel Gonzaga | KO/TKO | Round 1
- 2007 | UFC 70
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11
- Jędrzejczyk vs. Namajunas
- Rose Namajunas | KO/TKO | Round 1 | UFC 217
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12
- Usman vs. Edwards II
- Leon Edwards | KO/TKO | Round 5 | UFC 278
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13
- Penn vs. Edgar I
- Frankie Edgar | Decision | UFC 112
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14
- Griffin vs. Rua I
- Forrest Griffin | Submission | Round 3 | UFC 76
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15
- Sokoudjou vs. Nogueira
- Rameau Thierry Sokoudjou | KO/TKO | RD 1 | Pride 33
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16
- Couture vs. Sylvia
- Randy Couture | Decision | UFC 68
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17
- Randleman vs. Filipović I
- Kevin Randleman | KO/TKO | Round 1 | Pride Total Elimination 2004
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18
- Johnson vs. Cejudo II
- Henry Cejudo | Decision | UFC 227
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19
- Penn vs. Hughes I
- BJ Penn | Submission | Round 1 | UFC 46
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20
- Cruz vs. Garbrandt
- Cody Garbrandt | Decision | UFC 207